Infant botulism: is there an association with thiamine deficiency?

Reply to Rocke and Barker: The question is not whether birds are affected by thiamine deficiency or botulism, it is about the order of events

Contrary to the suggestion by Rocke and Barker (1), we do not want to exclude botulism as a part of the investigated wildlife disorder (2), because botulism may be secondary to the thiamine deficiency syndrome. This possibility and the investigations by Neimanis et al. (3) are discussed in Text S5 in our SI Appendix (2). Mörner et al. (4), who indeed examined paralyzed birds with respect to bot...

Beriberi (Thiamine Deficiency) and High Infant Mortality in Northern Laos

BACKGROUND Infantile beriberi (thiamine deficiency) occurs mainly in infants breastfed by mothers with inadequate intake of thiamine, typically among vulnerable populations. We describe possible and probable cases of infantile thiamine deficiency in northern Laos. METHODOLOGY/PRINCIPAL FINDINGS Three surveys were conducted in Luang Namtha Province. First, we performed a retrospective survey o...

یک مورد آنمی مگالوبلاستیک مقاوم پاسخ دهنده به تیامین

Thiamine responsive megaloblastic anemia (TRMA), also known as Roger syndrome is an autosomal recessive disorder resulting from the deficiency of thiamine (Vitamin B1) transporter protein. This is the report of a 3- year follow up of a female child who presented in 2000 at the age of 11 with severe anemia, congenital deafness and diabetes mellitus. In our follow-up period we prescribed 100-mg...

Characterization of Clostridium botulinum spores and its toxin in honey

Botulism is a serious paralytic disease caused by Clostridium botulinum toxin in foods. There are seven recognized serotypes of botulinum neurotoxins among which the principal prevalent types in humans include A, B and E. Infant botulism results from intestinal colonization and toxin production by C. botulinum spores in babies less than 1 year old. Honey is the most important food discriminated...

Constipation and poor feeding in an infant with botulism.